CAS No. 60166-93-0

Batch: Purity:99.86
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Iopamidol Chemical Structure
Chemical Structure
Check the Iopamidol product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

CAS Number 60166-93-0
Molecular Formula

C17H22I3N3O8
Molecular Weight (MW) 777.09
SMILES CC(C(=O)NC1=C(C(=C(C(=C1I)C(=O)NC(CO)CO)I)C(=O)NC(CO)CO)I)O

Ordering Information

Biological Activity

Iopamidol is a non-ionic, water-soluble triiodinated monomeric radiographic contrast agent. It increases attenuation of X-rays relative to surrounding tissues through its high-density iodine content, facilitating enhanced contrast visualization during radiological imaging. The compound functions as an extracellular fluid space marker, exhibiting low osmolality and reduced chemotoxicity in cellular and vascular compartments.

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 100 mg/mL (128.68 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Water 100 mg/mL
Ethanol Insoluble
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.