CAS No. 31842-01-0
Batch:
Purity:99.71
Chemical Structure
Check the
Indoprofen
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| CAS Number | 31842-01-0 | |
|---|---|---|
| Molecular Formula |
C17H15NO3 |
|
| Molecular Weight (MW) | 281.31 | |
| SMILES | CC(C1=CC=C(C=C1)N2CC3=CC=CC=C3C2=O)C(=O)O |
Indoprofen is a nonsteroidal anti-inflammatory drug and cyclooxygenase inhibitor that selectively increases survival motor neuron 2 (SMN2) reporter protein expression and elevates endogenous SMN protein levels. Activation of the PDK1/AKT signaling pathway by indoprofen promotes downstream cellular survival mechanisms, effectively preventing muscle wasting and muscle functional decline in aged mouse models. [1]
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
52 mg/mL
(184.84 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.