CAS No. 120-72-9
Batch:
Purity:99.95
Chemical Structure
Check the
Indole
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
Chemical Information
| CAS Number | 120-72-9 | |
|---|---|---|
| Molecular Formula |
C8H7N |
|
| Molecular Weight (MW) | 117.15 | |
| SMILES | C1=CC=C2C(=C1)C=CN2 |
Biological Activity
Indole is an aromatic heterocyclic bacterial signaling molecule produced by diverse commensal and pathogenic bacteria. It regulates intercellular signaling pathways involved in microbial physiology, suppressing biofilm formation, drug resistance, and virulence factor expression in pathogenic strains. Additionally, indole acts as an endogenous signaling metabolite that modulates host gut barrier integrity and immune responses through activation of nuclear receptor pathways. [1]
How to Prepare Stock Solution?
|
Concentration
Volume
Mass
|
|---|
Solubility
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
23 mg/mL
(196.32 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Reference
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Note: Technical data last updated: Sep 1, 2026.