CAS No. 487-89-8
Chemical Structure
Check the
Indole-3-carboxaldehyde
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
Chemical Information
| CAS Number | 487-89-8 | |
|---|---|---|
| Molecular Formula |
C9H7NO |
|
| Molecular Weight (MW) | 145.16 |
Biological Activity
Indole-3-carboxaldehyde (3-Formylindole) is a natural indole derivative and tryptophan metabolite that acts as a selective agonist of the aryl hydrocarbon receptor (AhR). Activation of the AhR signaling pathway by indole-3-carboxaldehyde stimulates mucosal interleukin-22 (IL-22) transcription and expression, which enhances intestinal epithelial barrier function and provides protection against gastrointestinal inflammation and opportunistic microbial infections. [1]
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Note: Technical data last updated: Sep 1, 2026.