Ilomastat (GM6001) is a potent, broad-spectrum matrix metalloproteinase (MMP) inhibitor. It affects EGFR and RhoA/Rac1 signaling pathways by blocking MMP-mediated extracellular matrix degradation and protein shedding, effectively inhibiting cell migration, invasion, and tissue remodeling.
Ilomastat (GM6001) IC50 for Cell-based and Cell-free Assays
Comprehensive IC50 Values for Ilomastat (GM6001) Across Cell-free Enzyme Inhibitory Profiles and Cell-based Functional Assays.