CAS No. 172152-36-2
Batch:
Purity:99.50
Chemical Structure
Check the
Ilaprazole
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | 2-[(4-methoxy-3-methyl-2-pyridinyl)methylsulfinyl]-6-pyrrol-1-yl-1H-benzimidazole | |
|---|---|---|
| CAS Number | 172152-36-2 | |
| Molecular Formula |
C19H18N4O2S |
|
| Molecular Weight (MW) | 366.44 | |
| SMILES | CC1=C(C=CN=C1CS(=O)C2=NC3=C(N2)C=C(C=C3)N4C=CC=C4)OC | |
| InChIKey | HRRXCXABAPSOCP-UHFFFAOYSA-N |
Ilaprazole is a potent proton pump inhibitor that targets gastric H+/K+-ATPase to suppress gastric acid secretion. By covalently binding to sulfhydryl groups of cysteine residues on the H+/K+-ATPase enzyme, ilaprazole blocks the terminal step of gastric acid production. This inhibition prevents hydrogen ion transport into the gastric lumen, suppressing basal and stimulated acid secretion and promoting gastric mucosal healing.
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Concentration
Volume
Mass
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|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
73 mg/mL
(199.21 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 14 mg/mL |
| Water | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.