CAS No. 2070014-98-9

Batch: Purity:99.09
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IFN alpha-IFNAR-IN-1 hydrochloride Chemical Structure
Chemical Structure
Check the IFN alpha-IFNAR-IN-1 hydrochloride product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

IUPAC Name N-methyl-1-(2-naphthalen-1-ylsulfanylphenyl)methanamine;hydrochloride
CAS Number 2070014-98-9
Molecular Formula

C18H17NS.ClH
Molecular Weight (MW) 315.86
InChIKey QTESJCPDPNGOLF-UHFFFAOYSA-N

Biological Activity

IFN alpha-IFNAR-IN-1 hydrochloride is a nonpeptidic, low-molecular-weight inhibitor that directly disrupts the protein-protein interaction between IFN-α and IFNAR. In murine bone-marrow-derived, Flt-L-differentiated plasmacytoid dendritic cell cultures, the compound suppresses modified Vaccinia virus ankara-induced IFN-α responses with an ICvalue of 2-. By blocking receptor interaction, this molecule effectively attenuates downstream interferon-mediated immune signaling pathways.

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 63 mg/mL (199.45 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Ethanol 63 mg/mL
Water 8 mg/mL
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.