CAS No. 58186-27-9

Batch: Purity:99.97
Idebenone Chemical Structure
Chemical Structure
Check the Idebenone product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

IUPAC Name 2-(10-hydroxydecyl)-5,6-dimethoxy-3-methylcyclohexa-2,5-diene-1,4-dione
CAS Number 58186-27-9
Molecular Formula

C19H30O5

Molecular Weight (MW) 338.44
SMILES CC1=C(C(=O)C(=C(C1=O)OC)OC)CCCCCCCCCCO
InChIKey JGPMMRGNQUBGND-UHFFFAOYSA-N

Ordering Information

Biological Activity

Idebenone (CV-2619) is a synthetic analog of coenzyme Q10 that acts as a potent antioxidant and mitochondrial electron transport chain facilitator. It effectively inhibits lipid peroxidation, protects cellular mitochondria against oxidative stress, and maintains mitochondrial energy production. By neutralizing free radicals and preserving mitochondrial membrane integrity, idebenone enhances cellular ATP synthesis and supports cell survival.

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 68 mg/mL (200.92 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Ethanol 68 mg/mL
Water Insoluble
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.