CAS No. 56725-99-6

Icariside I Chemical Structure
Chemical Structure
Check the Icariside I product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

CAS Number 56725-99-6
Molecular Formula

C27H30O11

Molecular Weight (MW) 530.52
SMILES COC1=CC=C(C=C1)C2=C(O)C(=O)C3=C(O2)C(=C(OC4OC(CO)C(O)C(O)C4O)C=C3O)CC=C(C)C

Ordering Information

Biological Activity

Icariside I is a natural flavonol glycoside isolated from Epimedii Folium that promotes cell proliferation and osteogenic differentiation. It modulates key signaling cascades, including Wnt/beta-catenin and BMP-2/Smad pathways, to upregulate osteogenic marker expression such as alkaline phosphatase and osteocalcin. These cellular downstream responses enhance extracellular matrix mineralization and support osteoblast maturation and bone tissue regeneration. [1]

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Note: Technical data last updated: Sep 1, 2026.