CAS No. 31121-93-4
Batch:
Purity:97.92
Chemical Structure
Check the
Ibuprofen sodium
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | sodium 2-[4-(2-methylpropyl)phenyl]propanoate | |
|---|---|---|
| CAS Number | 31121-93-4 | |
| Molecular Formula |
C13H18O2.Na |
|
| Molecular Weight (MW) | 229.27 | |
| InChIKey | PTTPUWGBPLLBKW-UHFFFAOYSA-M |
Ibuprofen sodium is an orally active nonsteroidal anti-inflammatory drug that acts as a selective inhibitor of COX-1. By inhibiting COX activity, it blocks the enzymatic conversion of arachidonic acid into prostaglandins, downstream reducing pro-inflammatory mediator synthesis. This suppression of prostaglandin signaling leads to anti-inflammatory, analgesic, and antipyretic phenotypes in cellular and animal models. [1]
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Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| Water | 46 mg/mL |
| Ethanol | 46 mg/mL |
| DMSO |
8 mg/mL
(34.89 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.