CAS No. 70-70-2

Batch: Purity:99.67
4'-Hydroxypropiophenone Chemical Structure
Chemical Structure
Check the 4'-Hydroxypropiophenone product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

CAS Number 70-70-2
Molecular Formula

C9H10O2

Molecular Weight (MW) 150.17
SMILES CCC(=O)C1=CC=C(C=C1)O

Ordering Information

Biological Activity

4'-Hydroxypropiophenone is a synthetic acetophenone derivative that acts as a gonadotropin inhibitor to suppress pituitary gonadotropic function. By inhibiting pituitary gonadotropin release, it disrupts downstream hypothalamic-pituitary-gonadal axis signaling, resulting in reduced luteinizing hormone and follicle-stimulating hormone levels. This action modulates endocrine signaling pathways and attenuates gonadotropin-mediated cell proliferation and hormonal signaling cascades in target tissues.

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 30 mg/mL (199.77 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.