CAS No. 1807530-05-7
Batch:
Purity:
Chemical Structure
Check the
Hydroxy-PEG4-O-Boc
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| CAS Number | 1807530-05-7 | |
|---|---|---|
| Molecular Formula |
C16H32O8 |
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| Molecular Weight (MW) | 352.42 | |
| SMILES | CC(C)(C)OC(=O)COCCOCCOCCOCCOCCO |
Hydroxy-PEG4-O-Boc is a PEG-based PROTAC linker utilized in the synthesis of proteolysis targeting chimeras (PROTACs). These bifunctional linkers covalently join a target protein ligand to an E3 ubiquitin ligase recruitment moiety, enabling the formation of a stable ternary complex. This induced proximity facilitates target protein polyubiquitination and subsequent degradation via the ubiquitin-proteasome system to modulate intracellular signaling pathways. [1]
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Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
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Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.