CAS No. 7400-08-0

Batch: Purity:99.93
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p-Hydroxy-cinnamic Acid Chemical Structure
Chemical Structure
Check the p-Hydroxy-cinnamic Acid product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

CAS Number 7400-08-0
Molecular Formula

C9H8O3
Molecular Weight (MW) 164.16
SMILES C1=CC(=CC=C1C=CC(=O)O)O

Ordering Information

Biological Activity

p-Hydroxy-cinnamic Acid is a phenolic acid derivative with in vitro antimalarial activity and in vivo anti-osteoporotic properties. It stimulates osteoblast differentiation and bone formation while suppressing osteoclastogenesis and bone resorption. Furthermore, p-Hydroxy-cinnamic Acid attenuates cellular oxidative stress and displays activity against Plasmodium parasites, effectively preventing bone loss in animal models. [1]

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 33 mg/mL (201.02 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Ethanol 33 mg/mL
Water Insoluble
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.