Molecular Weight: 380.47 g/mol

HPK1-IN-2 Chemical Structure
Chemical Structure
Check the HPK1-IN-2 product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 76 mg/mL (199.75 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Ethanol 10 mg/mL
Water Insoluble
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

Chemical Information

IUPAC Name 4-amino-5-[6-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]-7H-thieno[2,3-b]pyridin-6-one
CAS Number 2056122-11-1
Molecular Formula

C19H20N6OS
Molecular Weight (MW) 380.47
SMILES CN1CCN(CC1)C2=CC=C3N=C([NH]C3=C2)C4=C(N)C5=C(NC4=O)SC=C5
InChIKey WKFZMTSRRQSGEY-UHFFFAOYSA-N

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Note: Technical data last updated: Sep 1, 2026.