Home Immunology & Inflammation gp120/CD4 HIV Peptide T For research use only.

HIV Peptide T

Synonyms:

HIV Peptide T (Peptide T), a synthetic octapeptide and an antiviral agent for use in HIV infection, of which mechanism of action consists of competitive inhibition of the binding of gp120 (a surface protein of HIV) to the CD4 receptor, homologous binding to vasointestinal peptide (VIP) receptors, and blockade of cytokine production and function.

HIV Peptide T Chemical Structure

HIV Peptide T Chemical Structure

CAS: 106362-33-8

Purity & Quality Control

Batch: P113601 DMSO] 100 mg/mL] false] Water] 100 mg/mL] false] Ethanol] Insoluble] false Purity: 98.49%
98.49

HIV Peptide T Related Products

Choose Selective gp120/CD4 Inhibitors

Biological Activity

Description HIV Peptide T (Peptide T), a synthetic octapeptide and an antiviral agent for use in HIV infection, of which mechanism of action consists of competitive inhibition of the binding of gp120 (a surface protein of HIV) to the CD4 receptor, homologous binding to vasointestinal peptide (VIP) receptors, and blockade of cytokine production and function.
Targets
CD4-gp120 interactions [1]

Chemical Information & Solubility

Molecular Weight 857.86 Formula

C35H55N9O16
CAS No. 106362-33-8 SDF --
Density 95.0~105.0%
Smiles CC(N)C(=O)NC(CO)C(=O)NC(C(C)O)C(=O)NC(C(C)O)C(=O)NC(C(C)O)C(=O)NC(CC(N)=O)C(=O)NC(CC1=CC=C(O)C=C1)C(=O)NC(C(C)O)C(O)=O
Storage (From the date of receipt) 3 years-20°C powder

In vitro
Batch:

DMSO : 100 mg/mL ( (116.56 mM)； Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Water : 100 mg/mL

Ethanol : Insoluble


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In vivo
Batch:

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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