CAS No. 19202-36-9
Batch:
Purity:99.97
Chemical Structure
Check the
Hinokiflavone
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| CAS Number | 19202-36-9 | |
|---|---|---|
| Molecular Formula |
C30H18O10 |
|
| Molecular Weight (MW) | 538.46 |
Hinokiflavone is a natural plant biflavonoid that functions as a pre-mRNA splicing modulator by inhibiting the SUMO-specific protease SENP1. By suppressing SENP1 activity, it blocks spliceosome B complex assembly and elevates protein SUMOylation levels. Additionally, hinokiflavone induces apoptosis through Bax upregulation and Bcl-2 downregulation, while suppressing breast cancer cell migration and invasion by impairing the EMT signaling pathway. [1][2]
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
100 mg/mL
(185.71 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.