CAS No. 136-77-6
| IUPAC Name | 4-hexylbenzene-1,3-diol | |
|---|---|---|
| CAS Number | 136-77-6 | |
| Molecular Formula |
C12H18O2 |
|
| Molecular Weight (MW) | 194.27 | |
| SMILES | CCCCCCC1=C(C=C(C=C1)O)O | |
| InChIKey | WFJIVOKAWHGMBH-UHFFFAOYSA-N |
Hexylresorcinol is an organic alkylresorcinol derivative that acts as a potent inhibitor of mushroom tyrosinase, suppressing both monophenolase and diphenolase activities. By blocking the tyrosinase-mediated enzymatic conversion of L-tyrosine and L-DOPA in melanin biosynthesis pathways, it effectively reduces enzymatic browning and pigment formation. Consequently, this inhibition leads to decreased melanin accumulation and exhibits antiseptic, local anesthetic, and anthelmintic biological properties in cellular models. [1]
|
Concentration
Volume
Mass
|
|---|
| Solvent | Solubility & Note |
|---|---|
| DMSO |
38 mg/mL
(195.6 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 38 mg/mL |
| Water | Insoluble |
| DMSO |
39 mg/mL
(200.75 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
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