CAS No. 145459-19-4

Batch: Purity:99.93
Heterophyllin B Chemical Structure
Chemical Structure
Check the Heterophyllin B product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

CAS Number 145459-19-4
Molecular Formula

C40H58N8O8

Molecular Weight (MW) 778.94
SMILES CCC(C)C1C(=O)NC(C(=O)NCC(=O)NCC(=O)NC(C(=O)N2CCCC2C(=O)N3CCCC3C(=O)N4CCCC4C(=O)N1)CC(C)C)CC5=CC=CC=C5

Ordering Information

Biological Activity

Heterophyllin B is a naturally occurring cyclic peptide isolated from Pseudostellaria heterophylla with potential antitumor properties. It targets human esophageal cancer cells by suppressing cellular proliferation and inducing apoptosis. In vitro studies demonstrate that treatment with Heterophyllin B reduces cell viability and inhibits tumor growth, serving as a promising therapeutic candidate and novel strategy for the management of esophageal carcinoma.

How to Prepare Stock Solution?

Concentration Volume Mass
1 mg 5 mg 10 mg
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 100 mg/mL (128.37 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.