CAS No. 1435265-06-7
Batch:
Purity:99.41
Chemical Structure
Check the
HCH6-1
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | methyl (2R)-2-[[(2S)-2-benzamido-3-(1H-indol-3-yl)propanoyl]amino]-3-phenylpropanoate | |
|---|---|---|
| CAS Number | 1435265-06-7 | |
| Molecular Formula |
C28H27N3O4 |
|
| Molecular Weight (MW) | 469.53 | |
| SMILES | COC(=O)C(CC1=CC=CC=C1)NC(=O)C(CC2=CNC3=CC=CC=C32)NC(=O)C4=CC=CC=C4 | |
| InChIKey | MPFZAIDTRUPTSU-LOSJGSFVSA-N |
HCH6-1 is a selective competitive antagonist targeting formyl peptide receptor 1 (FPR1). By blocking FPR1 activation, HCH6-1 inhibits downstream signaling pathways involved in neutrophil recruitment and inflammatory responses. This inhibition suppresses excessive immune cell activation and confers protective effects against acute lung injury, highlighting its therapeutic potential for FPR1-mediated inflammatory lung diseases. [1]
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Concentration
Volume
Mass
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Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
94 mg/mL
(200.2 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 8 mg/mL |
| Water | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.