CAS No. 1492-24-6

Batch: Purity:99.4
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H-Abu-OH Chemical Structure
Chemical Structure
Check the H-Abu-OH product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

CAS Number 1492-24-6
Molecular Formula

C4H9NO2
Molecular Weight (MW) 103.12
SMILES CCC(C(=O)O)N

Biological Activity

H-Abu-OH (2-Aminobutyric acid) is a non-proteinogenic alpha-amino acid that functions as a substrate for nonribosomal peptide synthases and biosynthetic enzymes. By acting as an alternative building block in nonribosomal peptide synthesis and glutathione-related pathways, it promotes the assembly of specialized peptide derivatives and influences cellular antioxidant metabolite pools, such as ophthalmic acid during metabolic stress. [1]

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
Water 10 mg/mL
DMSO Insoluble
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.)
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

Reference

[1] Soga T, et al. J Biol Chem. 2006;281(24):16768-76.

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Note: Technical data last updated: Sep 1, 2026.