CAS No. 265129-71-3
Batch:
Purity:98.58
Chemical Structure
Check the
GW7647
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | 2-[4-[2-[4-cyclohexylbutyl(cyclohexylcarbamoyl)amino]ethyl]phenyl]sulfanyl-2-methylpropanoic acid | |
|---|---|---|
| CAS Number | 265129-71-3 | |
| Molecular Formula |
C29H46N2O3S |
|
| Molecular Weight (MW) | 502.75 | |
| SMILES | CC(C)(SC1=CC=C(CCN(CCCCC2CCCCC2)C(=O)NC3CCCCC3)C=C1)C(O)=O | |
| InChIKey | PKNYXWMTHFMHKD-UHFFFAOYSA-N |
GW7647 is a potent peroxisome proliferator-activated receptor alpha (PPARα) agonist that selectively activates human PPARα over PPARγ and PPARδ. Activation of PPARα by GW7647 regulates gene transcription involved in lipid metabolism and fatty acid oxidation. In cell-based assays, GW7647 stimulates PPARα-mediated transcriptional activity, modulating metabolic signaling pathways and cellular lipid homeostasis.
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Concentration
Volume
Mass
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Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
100 mg/mL
(198.9 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 25 mg/mL |
| Water | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.