CAS No. 83797-69-7
Batch:
Purity:99.96
Chemical Structure
Check the
6-OAU
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | 6-(octylamino)-1H-pyrimidine-2,4-dione | |
|---|---|---|
| CAS Number | 83797-69-7 | |
| Molecular Formula |
C12H21N3O2 |
|
| Molecular Weight (MW) | 239.31 | |
| SMILES | CCCCCCCCNC1=CC(=O)NC(=O)N1 | |
| InChIKey | PFSWASUQURIOOR-UHFFFAOYSA-N |
6-OAU is a surrogate agonist of G protein-coupled receptor 84 (GPR84) that activates human GPR84 signaling. Engagement of GPR84 by 6-OAU stimulates downstream intracellular pathways, promoting pro-inflammatory responses and leukocyte activation. Through GPR84 activation, 6-OAU serves as a functional tool compound for investigating GPR84-mediated metabolic and inflammatory signaling pathways in immune and inflammatory cell phenotypes.
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Concentration
Volume
Mass
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Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
35 mg/mL
(146.25 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.