CAS No. 61371-55-9
Batch:
Purity:98.23
Chemical Structure
Check the
Griffonilide
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| CAS Number | 61371-55-9 | |
|---|---|---|
| Molecular Formula |
C8H8O4 |
|
| Molecular Weight (MW) | 168.15 | |
| SMILES | C1=CC2=CC(=O)OC2C(C1O)O |
Griffonilide is a natural product lactone that functions as a bioactive agent involved in bone remodeling activity. It modulates downstream signaling pathways that regulate osteoblast and osteoclast functions, leading to structural modifications within the skeletal matrix. These cellular responses ultimately drive structural tissue remodeling and modulate bone matrix turnover dynamics. [1]
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
34 mg/mL
(202.2 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.