SMILES:

CN1N=CC2=CC(=CN=C2C1=O)C3=CC(=C(F)C=C3C)NC(=O)C4=CC(=CC=C4)C(C)(C)C#N
GNE-9815 Chemical Structure
Chemical Structure
Check the GNE-9815 product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

IUPAC Name 3-(2-cyanopropan-2-yl)-N-[2-fluoro-4-methyl-5-(7-methyl-8-oxopyrido[2,3-d]pyridazin-3-yl)phenyl]benzamide
CAS Number 2729996-45-4
Molecular Formula

C26H22FN5O2
Molecular Weight (MW) 455.48
SMILES CN1N=CC2=CC(=CN=C2C1=O)C3=CC(=C(F)C=C3C)NC(=O)C4=CC(=CC=C4)C(C)(C)C#N
InChIKey SXCTZLXYGLXXRY-UHFFFAOYSA-N

How to Prepare Stock Solution?

Concentration Volume Mass
🧮 Molarity Calculator

Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 30 mg/mL (65.86 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Ethanol 5 mg/mL
Water Insoluble
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.