CAS No. 76135-82-5

Glucosyl-vitexin Chemical Structure
Chemical Structure
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Chemical Information

IUPAC Name 5,7-dihydroxy-8-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-2-[4-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]chromen-4-one
CAS Number 76135-82-5
Molecular Formula

C27H30O16

Molecular Weight (MW) 610.52
InChIKey FIKSWIOVRVHXGQ-TUTGZWPLSA-N

Biological Activity

Glucosyl-vitexin is a naturally occurring C-glycosylflavone derivative isolated from millet that acts as an inhibitor of thyroid peroxidase (TPO). By suppressing TPO-mediated iodination and coupling reactions during thyroid hormone biosynthesis, glucosyl-vitexin disrupts the production of thyroxine and triiodothyronine. This inhibition impairs thyroid gland function, contributing to anti-thyroid cellular responses and goitrogenic effects in thyroid tissue. [1]

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Note: Technical data last updated: Sep 1, 2026.