CAS No. 51-77-4
Batch:
Purity:
Chemical Structure
Check the
Gefarnate
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
Chemical Information
| CAS Number | 51-77-4 | |
|---|---|---|
| Molecular Formula |
C27H44O2 |
|
| Molecular Weight (MW) | 400.64 | |
| SMILES | CC(=CCCC(=CCCC(=CCCC(=O)OCC=C(C)CCC=C(C)C)C)C)C |
Biological Activity
Gefarnate is a synthetic terpene-based anti-ulcer compound that acts as a gastric mucosal protective agent. It stimulates endogenous prostaglandin synthesis and enhances gastric mucin secretion, strengthening the gastroduodenal mucus-bicarbonate barrier. By bolstering mucosal defense mechanisms and preventing mucosal degradation, gefarnate protects gastric epithelial tissue against acid- and pepsin-induced damage to support mucosal integrity. [1][2]
How to Prepare Stock Solution?
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Concentration
Volume
Mass
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Solubility
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
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Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Reference
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Note: Technical data last updated: Sep 1, 2026.