CAS No. 1978336-61-6

Batch: Purity:99.85
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GB1107 Chemical Structure
Chemical Structure
Check the GB1107 product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

IUPAC Name (2R,3R,4S,5R,6R)-2-(3,4-dichlorophenyl)sulfanyl-6-(hydroxymethyl)-4-[4-(3,4,5-trifluorophenyl)triazol-1-yl]oxane-3,5-diol
CAS Number 1978336-61-6
Molecular Formula

C20H16Cl2F3N3O4S
Molecular Weight (MW) 522.32
SMILES OCC1OC(SC2=CC=C(Cl)C(=C2)Cl)C(O)C(C1O)[N]3C=C(N=N3)C4=CC(=C(F)C(=C4)F)F
InChIKey CSGJIUAIYDKFPC-DABHTEOTSA-N

Ordering Information

Biological Activity

GB1107 is a potent and selective inhibitor of galectin-3 (Gal-3). By blocking the carbohydrate-recognition domain of Gal-3, it disrupts Gal-3-mediated protein interactions and downstream oncogenic signaling pathways. Target inhibition alters tumor microenvironment dynamics, suppresses cell proliferation, migration, and invasion, and restores immune surveillance by enhancing anti-tumor T-cell responses in preclinical models. [1][2]

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 100 mg/mL (191.45 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Ethanol 100 mg/mL
Water Insoluble
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.