CAS No. 107390-08-9
Chemical Structure
Check the
Garcinone D
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
Chemical Information
| IUPAC Name | 1,3,6-trihydroxy-8-(3-hydroxy-3-methylbutyl)-7-methoxy-2-(3-methylbut-2-enyl)xanthen-9-one | |
|---|---|---|
| CAS Number | 107390-08-9 | |
| Molecular Formula |
C24H28O7 |
|
| Molecular Weight (MW) | 428.47 | |
| InChIKey | TYALNCRUIKOKGP-UHFFFAOYSA-N |
Biological Activity
Garcinone D is a natural xanthone that functions as an activator of the STAT3/Cyclin D1 and Nrf2/HO-1 signaling pathways and an inhibitor of the CDK2/Cyclin E1 complex. Activation of STAT3 and Nrf2/HO-1 promotes neural stem cell proliferation and enhances cellular antioxidant pathways. Additionally, suppression of CDK2/Cyclin E1 signaling blocks tumor cell cycle progression in prostate and breast cancer models. [1]
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Note: Technical data last updated: Sep 1, 2026.