Ganciclovir sodium Clinical Trials

Size	Price	Qty
25mg	USD 147
100mg	USD 297

Clinical Trials

Numerous clinical trials evaluate ganciclovir and its sodium salt, primarily for cytomegalovirus prevention and management in kidney, pancreas, and heart transplantation, as well as EBV-associated lymphomas, lymphoproliferative disorders, pneumonia, acute respiratory failure, and HIV coinfections. Ranging from Phase 1 through Phase 4 with statuses from recruiting to completed or terminated, these studies assess drug safety and efficacy across diverse populations. Research sponsors include academic institutions like the Fred Hutchinson Cancer Center and University of Wisconsin Madison, alongside industry partners such as Hoffmann-La Roche and Merck Sharp & Dohme.

NCT Number	Recruitment	Conditions	Sponsor/Collaborators	Start Date	Phases
NCT07513623	NOT_YET_RECRUITING	Cytomegalovirus (CMV); Anterior Uveitis; Infectious Uveitis; CMV Infection	University of California, San Francisco	2026-11-01	PHASE2
NCT06798909	RECRUITING	Cytomegalovirus (CMV); Kidney Transplant; Complications; Kidney Diseases	University of California, San Francisco	2025-07-22	PHASE3
NCT07294547	RECRUITING	Kidney Transplantation, Cytomegalovirus Infections; EBV Infection; Antiviral Prophylaxis	National Taiwan University Hospital	2025-11-27
NCT06102525	RECRUITING	Glioblastoma	Rznomics, Inc.	2024-10-08	PHASE1; PHASE2
NCT07450365	NOT_YET_RECRUITING	Congenital CMV Infection	Hu Bofei	2026-02-15	PHASE4
NCT06574789	RECRUITING	Cytomegalovirus Viraemia	Murdoch Childrens Research Institute	2024-10-29	PHASE2
NCT06853184	RECRUITING	CMV Infection	Amivas Inc.	2025-08-01	PHASE2
NCT07383649	RECRUITING	Brain Cancer Metastatic; CMV Viremia	The Methodist Hospital Research Institute	2026-07-14	PHASE2
NCT07079735	RECRUITING	CMV Viremia; Heart Transplant Infection; Heart Transplant Failure and Rejection	Columbia University	2025-09-12	PHASE2; PHASE3
NCT04116411	ACTIVE_NOT_RECRUITING	Glioblastoma Multiforme	Cecilia Soderberg-Naucler	2019-09-04	PHASE2
NCT06334497	RECRUITING	Cytomegalovirus Infection	Assistance Publique - Hôpitaux de Paris	2024-08-14	PHASE3
NCT07235683	RECRUITING	CMV; Lung Transplant Recipient	University Health Network, Toronto	2025-12-24	PHASE4
NCT05911503	RECRUITING	Cytomegalovirus Retinitis; Ganciclovir Eye Drops	Tianjin Medical University	2023-07-01	EARLY_PHASE1
NCT05708755	RECRUITING	Lung Transplant; Complications	NYU Langone Health	2024-09-13	PHASE2
NCT06057194	NOT_YET_RECRUITING	Infections, Cytomegalovirus	Maimónides Biomedical Research Institute of Córdoba	2023-10	PHASE2
NCT07379203	NOT_YET_RECRUITING	Cytomegalovirus (CMV) Infection	Wits Health Consortium (Pty) Ltd	2026-02-01	PHASE2
NCT06439342	RECRUITING	Cytomegalovirus (CMV)	Takeda	2024-12-16	PHASE3
NCT07266467	RECRUITING	Kidney Transplant	First Affiliated Hospital Xi'an Jiaotong University	2025-05-13	PHASE4
NCT00092222	ACTIVE_NOT_RECRUITING	Lymphoproliferative Disorder; HHV-8; Malignancy; HIV	National Cancer Institute (NCI)	2004-10-28	PHASE2
NCT06436534	RECRUITING	Rhinitis, Allergic	Union Hospital, Tongji Medical College, Huazhong University of Science and Technology	2024-05-24
NCT07138989	NOT_YET_RECRUITING	Nasopharyngeal Cancinoma (NPC)	Sun Yat-sen University	2025-08-19	PHASE2
NCT04724447	COMPLETED	Major Depressive Disorder	Laureate Institute for Brain Research, Inc.	2021-11-23	PHASE1; PHASE2
NCT06391918	TERMINATED	Solid Tumor, Adult	GenVivo, Inc.	2024-03-04	PHASE1
NCT06971913	NOT_YET_RECRUITING	SLE (Systemic Lupus); CMV	Peking University People's Hospital	2025-05-20	PHASE2
NCT06034925	COMPLETED	Transplant Complication; CMV	Medical University of South Carolina	2023-11-06	PHASE4
NCT05041426	COMPLETED	Lung Transplant; CMV	Fernanda P Silveira, MD, MS	2021-12-06	PHASE2
NCT06341686	UNKNOWN	CMV Infection	Hospital do Rim e Hipertensão	2024-05-05	PHASE3
NCT03915366	COMPLETED	Pneumonia; HIV/AIDS; Tuberculosis; Cytomegalovirus Infections	Hospital Universitario 12 de Octubre	2020-03-01	PHASE2; PHASE3
NCT06302140	TERMINATED	Advanced Cancer	Viracta Therapeutics, Inc.	2024-02-28	PHASE1
NCT05011058	TERMINATED	Epstein-Barr Virus Associated Lymphoma; EBV-Positive DLBCL, NOS; EBV-Related Non-Hodgkin Lymphoma; EBV Related PTCL, NOS; EBV-Related Hodgkin Lymphoma; EBV-Related PTLD; EBV-Related Lymphoproliferative Disorder	Viracta Therapeutics, Inc.	2021-05-28	PHASE2
NCT06757907	COMPLETED	Herpetic Keratitis	Al-Azhar University	2024-10-01
NCT03586284	TERMINATED	Cytomegalovirus Anterior Uveitis	University of California, San Francisco	2020-03-15	PHASE2; PHASE3
NCT05166577	TERMINATED	Nasopharyngeal Carcinoma; EBV-Related Gastric Carcinoma; EBV-Related Leiomyosarcoma; EBV Related Carcinoma; EBV-Related Sarcoma	Viracta Therapeutics, Inc.	2021-10-08	PHASE1
NCT04706507	TERMINATED	Acute Respiratory Failure	Fred Hutchinson Cancer Center	2021-06-29	PHASE3
NCT06407232	Not yet recruiting	Cytomegalovirus Infections\|Kidney Transplant Infection\|Pancreas Transplant	University of Wisconsin Madison\|Merck Sharp & Dohme LLC	2024-05	Phase 3
NCT05578820	COMPLETED	Sarcoma; Melanoma; Squamous Cell Carcinoma of Head and Neck; Breast Neoplasms; Uterine Cervical Neoplasms; Vulvar Neoplasms; Penile Neoplasms; Anus Neoplasms	Gene Surgery LLC	2022-01-01	PHASE1
NCT02943057	COMPLETED	Cytomegalovirus Infections	Singapore National Eye Centre	2016-10	PHASE4
NCT04064697	TERMINATED	Ulcerative Colitis, Unspecified	Centre Hospitalier Universitaire de Saint Etienne	2021-04-22	PHASE3
NCT06057194	Not yet recruiting	Infections Cytomegalovirus	Maimónides Biomedical Research Institute of Córdoba\|MERCK SHARP & DOHME DE ESPAÑA S.A.	2023-10	Phase 2
NCT03699254	COMPLETED	Transplantation Infection; Cytomegalovirus Infections	Maimónides Biomedical Research Institute of Córdoba	2019-04-05	PHASE3
NCT03397706	COMPLETED	Epstein-Barr Virus-Associated Lymphoma; Lymphoproliferative Disorders	Viracta Therapeutics, Inc.	2018-03-29	PHASE1; PHASE2
NCT03107871	TERMINATED	Cmv Congenital; CMV; Congenital Cmv; SNHL; Sensorineural Hearing Loss	Albert Park	2018-08-31	PHASE2
NCT02927067	COMPLETED	Cytomegalovirus (CMV)	Shire	2017-04-14	PHASE3
NCT03443869	COMPLETED	CMV Disease	Merck Sharp & Dohme LLC	2018-05-03	PHASE3
NCT03004261	COMPLETED	Cytomegalovirus Infections; Hematological Disease	Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine	2016-11	PHASE4
NCT04706507	Recruiting	Acute Respiratory Failure	Fred Hutchinson Cancer Center\|National Heart Lung and Blood Institute (NHLBI)	2021-06-29	Phase 3
NCT01972035	COMPLETED	Transplantation Infection; Epstein-Barr Virus Infections; Cytomegalovirus Infections	University of Minnesota	2014-08-01	PHASE2
NCT04225780	UNKNOWN	Cytomegalovirus Infections	Peking University People's Hospital	2020-02-01	PHASE1; PHASE2
NCT03301415	TERMINATED	Congenital Cytomegalovirus Infection	National Institute of Allergy and Infectious Diseases (NIAID)	2019-08-21	PHASE2
NCT04478474	Completed	Cytomegalovirus Infections	New York Medical College\|Merck Sharp & Dohme LLC	2020-09-15	--
NCT02931539	COMPLETED	Cytomegalovirus (CMV)	Shire	2016-12-22	PHASE3
NCT02871401	COMPLETED	Idiopathic Pulmonary Fibrosis	Vanderbilt University Medical Center	2018-01-03	PHASE1
NCT01649869	COMPLETED	Cytomegalovirus Infection	National Institute of Allergy and Infectious Diseases (NIAID)	2015-02-24	PHASE2
NCT03296553	COMPLETED	Kaposi Sarcoma; Human Immunodeficiency Virus; Immune Reconstitution Syndrome	National Institute of Cancerología	2015-10-01	PHASE2
NCT03217474	UNKNOWN	Herpes Simplex Keratitis	Chunxiao Wang	2017-07-20
NCT03631316	COMPLETED	Kidney Transplantation; Cytomegalovirus Infections; Pharmacokinetics; Therapeutic Equivalency	Luis Eduardo Morales Buenrostro	2018-03-01
NCT02606266	TERMINATED	Congenital Cytomegalovirus (CMV)	Assistance Publique - Hôpitaux de Paris	2017-07-11	PHASE2; PHASE3
NCT01552369	COMPLETED	Cytomegalovirus Infection	National Institute of Allergy and Infectious Diseases (NIAID)	2012-10-29	PHASE4
NCT01441063	COMPLETED	Castleman Disease; Multicentric Castleman Disease; Giant Lymph Node Hyperplasia	National Cancer Institute (NCI)	2011-09-13	PHASE2
NCT02005822	COMPLETED	Congenital Cytomegalovirus Infection; Sensorineural Hearing Loss	Dr. Ann C.T.M. Vossen	2013-10-22	PHASE3
NCT03698435	Unknown status	Cytomegalovirus Infections	University Medical Center Groningen	2018-05-25	--
NCT02152358	COMPLETED	Viral Pneumonia	Assistance Publique Hopitaux De Marseille	2014-02-05	PHASE4
NCT03598452	COMPLETED	Infection Viral; Uveitis, Posterior	Aier School of Ophthalmology, Central South University	2014-01
NCT02761291	UNKNOWN	Nasopharyngeal Carcinoma	Chang Gung Memorial Hospital	2016-05	PHASE1
NCT02370758	COMPLETED	Cytomegalovirus Viraemia	University Health Network, Toronto	2014-11
NCT01335932	COMPLETED	Acute Lung Injury; Acute Respiratory Distress Syndrome; Respiratory Failure	Fred Hutchinson Cancer Center	2011-03-10	PHASE2
NCT02439957	TERMINATED	Cytomegalovirus Disease; Kidney Transplant Infection	Jazz Pharmaceuticals	2015-09	PHASE3
NCT02439970	TERMINATED	Cytomegalovirus Disease	Jazz Pharmaceuticals	2015-09	PHASE3
NCT00372229	COMPLETED	Cytomegalovirus Infections	Hoffmann-La Roche	2006-05	PHASE3
NCT01663740	COMPLETED	Cytomegalovirus Infections	Hoffmann-La Roche	2012-01-30	PHASE4
NCT02503982	COMPLETED	Infection in Solid Organ Transplant Recipients	Rabin Medical Center	2014-12	PHASE4
NCT01255644	COMPLETED	Chronic Lymphocytic Leukemia	Medical University of Vienna	2010-12	PHASE4
NCT01611974	COMPLETED	Cytomegalovirus (CMV)	Shire	2012-07-17	PHASE2
NCT01533480	COMPLETED	Keratoconjunctivitis Due to Adenovirus; Viral Shedding	Lifelong Vision Foundation	2012-01	PHASE4
NCT01509404	COMPLETED	Cytomegalovirus Disease	Medical University of South Carolina	2011-11	PHASE4
NCT01446445	COMPLETED	Infection in Solid Organ Transplant Recipients	Nuria Lloberas	2011-12	PHASE4
NCT01329185	COMPLETED	EBV Viremia; CMV Viremia	University of Minnesota	2011-06	PHASE2
NCT01503918	COMPLETED	Critical Illness	University Hospital Birmingham NHS Foundation Trust	2012-01	PHASE2
NCT00828503	UNKNOWN	Cytomegalovirus Disease	Marcus Saemann	2008-12	PHASE2
NCT01655212	TERMINATED	Congenital Cytomegalovirus Infection; Sensorineural Hearing Loss	Dr. Ann C.T.M. Vossen	2012-06	PHASE3
NCT01165580	COMPLETED	Cytomegalovirus Infections, Heart Transplantation	Hoffmann-La Roche	2011-05	PHASE1
NCT00986557	UNKNOWN	Graft Versus Host Disease; Nonneoplastic Condition	University Hospital Birmingham	2009-09	PHASE2
NCT01647529	COMPLETED	Cytomegalovirus Anterior Segment Infection; Anterior Uveitis; Endotheliitis	Singapore National Eye Centre	2012-07
NCT01376804	COMPLETED	Kidney Transplantation, Cytomegalovirus Infections	Hoffmann-La Roche	2011-07-31	PHASE4
NCT01185223	TERMINATED	Allogeneic Stem Cell Transplantation	Pierrel Research Europe GmbH	2010-09	PHASE3
NCT01600365	UNKNOWN	Conjunctivitis; Adenovirus.	Adapt Produtos Oftalmológicos Ltda.	2012-05	PHASE3
NCT00966836	UNKNOWN	Heart Transplantation; Cardiac Allograft Vasculopathy; Cytomegalovirus Infection	University of Bologna	2009-04	PHASE3
NCT00947141	COMPLETED	Viraemia	University College, London	2003-02	PHASE4
NCT00466817	COMPLETED	Cytomegalovirus Infection	National Institute of Allergy and Infectious Diseases (NIAID)	2008-06	PHASE3
NCT02202564	COMPLETED	Liver Cancer; Hepatocellular Carcinoma	Huazhong University of Science and Technology	2006-10	PHASE2
NCT02297854	COMPLETED	Healthy	Dr. Reddy's Laboratories Limited	2011-07	PHASE1
NCT02296723	COMPLETED	Healthy	Dr. Reddy's Laboratories Limited	2011-07	PHASE1
NCT00964756	COMPLETED	Ovarian Cancer	University of Alabama at Birmingham	2009-08	PHASE1
NCT00992732	TERMINATED	Lymphoid Malignancies; Lymphoproliferative Disorders	HemaQuest Pharmaceuticals Inc.	2010-05	PHASE2
NCT00093704	TERMINATED	Lymphoma; Lymphoproliferative Disorder	Jonsson Comprehensive Cancer Center	2005-03	PHASE1
NCT00001328	COMPLETED	Brain Neoplasm; Neoplasm Metastasis	National Institute of Neurological Disorders and Stroke (NINDS)	1992-08-21	PHASE1
NCT00330018	COMPLETED	Bone Marrow Transplantation; Cytomegalovirus	Hadassah Medical Organization	2006-02	PHASE3
NCT00530218	COMPLETED	Myelodysplastic/Myeloproliferative Neoplasm, Unclassifiable; Leukemia; Lymphoma; Multiple Myeloma; MDS; Myelodysplastic/Myeloproliferative Diseases	City of Hope Medical Center	1999-03	PHASE2
NCT01349452	COMPLETED	Conjunctivitis, Viral; Adenoviridae Infections	Federal University of São Paulo	2009-08
NCT00497796	COMPLETED	Cytomegalovirus Infections	Shire	2007-07-23	PHASE3
NCT00386412	COMPLETED	Cytomegalovirus Infection	PETHEMA Foundation	2005-11	PHASE2
NCT00917826	TERMINATED	EBV Lymphomas; Lympho-proliferative Diseases	HemaQuest Pharmaceuticals Inc.	2008-09	PHASE2
NCT00361933	WITHDRAWN	Giant Lymph Node Hyperplasia	University of Washington	2008-12	PHASE4
NCT00264290	COMPLETED	HIV Infections; Cytomegalovirus Infections	University of California, San Francisco	2006-08	PHASE4
NCT00294515	COMPLETED	Cytomegalovirus Infections	Hoffmann-La Roche	2006-03-31	PHASE3
NCT00431353	COMPLETED	Cytomegalovirus Infections	Hoffmann-La Roche	2004-04	PHASE4
NCT00400322	COMPLETED	Glioblastoma Multiforme; Cytomegalovirus Infection	Karolinska Institutet	2006-08
NCT00227370	COMPLETED	Cytomegalovirus Infections	Duke University	2003-07	PHASE3
NCT00096538	COMPLETED	Sarcoma	Memorial Sloan Kettering Cancer Center	2004-04
NCT00387530	WITHDRAWN	Gastric Cancer; Head and Neck Cancer; Lymphoma; Lymphoproliferative Disorder	University of California, San Diego	2006-05	PHASE2
NCT00241345	TERMINATED	Cytomegalovirus Infections	Washington University School of Medicine	2004-06	PHASE3
NCT00478465	COMPLETED	Chronic Fatigue Syndrome	Stanford University	2007-05	PHASE1; PHASE2
NCT00189150	COMPLETED	Kidney Transplant Recipient; Heart Transplant Recipient	University of Michigan	2005-04	PHASE4
NCT00730769	COMPLETED	Cytomegalovirus Infection	Salvador Gil-Vernet	2004-03	PHASE4
NCT00031434	COMPLETED	Cytomegalovirus Infections	National Institute of Allergy and Infectious Diseases (NIAID)	2002-07	PHASE1; PHASE2
NCT00716911	COMPLETED	Chronic Myeloproliferative Disorders; Leukemia; Lymphoma; Multiple Myeloma and Plasma Cell Neoplasm; Myelodysplastic Syndromes; Myelodysplastic/Myeloproliferative Neoplasms; Nonneoplastic Condition	City of Hope Medical Center	2000-01
NCT00275665	COMPLETED	Bone Marrow Stem Cell Transplant	Mayo Clinic	2001-11	PHASE3
NCT00034385	COMPLETED	Kidney Trasplant	National Institutes of Health Clinical Center (CC)	2002-04-24	PHASE4
NCT00141037	COMPLETED	Kidney Diseases; Kidney Transplantation; Kidney Transplant; Renal Transplantation; Renal Transplant	National Institute of Allergy and Infectious Diseases (NIAID)	2004-03	PHASE1; PHASE2
NCT00377741	COMPLETED	Cytomegalovirus Infections	Hoffmann-La Roche	2004-12	PHASE1
NCT00014911	COMPLETED	Diabetes Mellitus, Insulin-Dependent	National Institute of Allergy and Infectious Diseases (NIAID)	2001-04	PHASE2
NCT00090766	COMPLETED	Cytomegalovirus Infections	Hoffmann-La Roche	2004-05	PHASE2; PHASE3
NCT00194467	COMPLETED	Human Herpesvirus 8	University of Washington	2002-12	PHASE2
NCT00023231	COMPLETED	End-Stage Renal Disease	National Institute of Allergy and Infectious Diseases (NIAID)	2001-02
NCT00006264	COMPLETED	Lymphoma	AIDS Malignancy Consortium	2000-07	PHASE2
NCT00002377	COMPLETED	Cytomegalovirus Retinitis; HIV Infections	Hoffmann-La Roche	1997-01	PHASE3
NCT00006340	COMPLETED	Leukemia; Lymphoma; Precancerous Condition; Small Intestine Cancer	Boston Medical Center	1994-12	PHASE1
NCT00000143	COMPLETED	Cytomegalovirus Retinitis; HIV Infections	Johns Hopkins Bloomberg School of Public Health	1997-05	PHASE3
NCT00000894	COMPLETED	Cytomegalovirus Retinitis; HIV Infections	National Institute of Allergy and Infectious Diseases (NIAID)		PHASE4
NCT00000766	COMPLETED	Cytomegalovirus Retinitis; HIV Infections	National Institute of Allergy and Infectious Diseases (NIAID)		PHASE2
NCT00000134	COMPLETED	HIV Infections; Acquired Immunodeficiency Syndrome; Cytomegalovirus Retinitis	Johns Hopkins Bloomberg School of Public Health	1992-12	PHASE3
NCT00000688	COMPLETED	Cytomegalovirus Retinitis; HIV Infections	National Institute of Allergy and Infectious Diseases (NIAID)		PHASE3
NCT00000665	COMPLETED	Cytomegalovirus Retinitis; HIV Infections	National Institute of Allergy and Infectious Diseases (NIAID)
NCT00000136	COMPLETED	HIV Infections; Cytomegalovirus Retinitis	Johns Hopkins Bloomberg School of Public Health	1990-03	PHASE3
NCT00002096	COMPLETED	Cytomegalovirus Infections; HIV Infections	Hoffmann-La Roche		PHASE1
NCT00002299	COMPLETED	Cytomegalovirus Retinitis; HIV Infections	Hoffmann-La Roche
NCT00002015	COMPLETED	Cytomegalovirus Retinitis; HIV Infections	Roche Global Development
NCT00000970	COMPLETED	Cytomegalovirus Retinitis; HIV Infections	National Institute of Allergy and Infectious Diseases (NIAID)		PHASE1
NCT00017784	UNKNOWN	Cytomegalovirus Retinitis; HIV Infections	Hoffmann-La Roche		PHASE3
NCT00000989	COMPLETED	Cytomegalovirus Retinitis; HIV Infections	National Institute of Allergy and Infectious Diseases (NIAID)
NCT00562770	COMPLETED	Chronic Lymphocytic Leukemia; Leukemia	M.D. Anderson Cancer Center	2003-09	PHASE2
NCT00001100	COMPLETED	Cytomegalovirus Infections	National Institute of Allergy and Infectious Diseases (NIAID)		PHASE3
NCT00002156	COMPLETED	Cytomegalovirus Retinitis; HIV Infections	Ionis Pharmaceuticals, Inc.		PHASE2
NCT00001999	COMPLETED	Cytomegalovirus Retinitis; HIV Infections	American National Red Cross
NCT00373165	COMPLETED	DNA Virus Infection; Herpesviridae Infections; Cytomegalovirus Infection	Lower Saxony Center for Nephrology	2000-08	PHASE4
NCT00000668	COMPLETED	Cytomegalovirus Retinitis; HIV Infections	National Institute of Allergy and Infectious Diseases (NIAID)		PHASE1
NCT00566072	COMPLETED	Cytomegalovirus Infections	University Hospital, Ghent	2001-05
NCT00002034	COMPLETED	Cytomegalovirus Retinitis; HIV Infections	Hoffmann-La Roche
NCT00217503	COMPLETED	Lymphoma	National Cancer Institute (NCI)	2005-07	PHASE2
NCT00002251	COMPLETED	Cytomegalovirus Infections; HIV Infections	Hoffmann-La Roche
NCT00004278	COMPLETED	Cytomegalovirus Infections	National Center for Research Resources (NCRR)	1991-12	PHASE3
NCT00006480	COMPLETED	Neuroblastoma	Fred Hutchinson Cancer Center	2000-05	PHASE1
NCT00005057	COMPLETED	Melanoma (Skin)	National Human Genome Research Institute (NHGRI)	2000-03	PHASE1
NCT00000673	COMPLETED	Cytomegalovirus Retinitis; HIV Infections	National Institute of Allergy and Infectious Diseases (NIAID)		PHASE1
NCT00001061	COMPLETED	Cytomegalovirus Retinitis; HIV Infections	National Institute of Allergy and Infectious Diseases (NIAID)		PHASE2
NCT00002025	COMPLETED	Cytomegalovirus Infections; Cytomegalovirus Retinitis; HIV Infections	Hoffmann-La Roche
NCT00002330	COMPLETED	Cytomegalovirus Retinitis; HIV Infections	Roche Global Development
NCT00237653	TERMINATED	Cytomegalovirus Infections; Inflammatory Bowel Diseases	University Hospital, Grenoble	2004-02	PHASE3
NCT00002095	COMPLETED	Cytomegalovirus Infections; HIV Infections	Hoffmann-La Roche
NCT00275314	TERMINATED	Kidney Transplant	University of Pittsburgh	2006-02	PHASE3
NCT00002321	COMPLETED	Cytomegalovirus Retinitis; HIV Infections	Chiron Corporation		PHASE1
NCT00000995	COMPLETED	Cytomegalovirus Infections; HIV Infections	National Institute of Allergy and Infectious Diseases (NIAID)
NCT00002301	UNKNOWN	Cytomegalovirus Retinitis; HIV Infections	Astra USA
NCT00002257	COMPLETED	Cytomegalovirus Retinitis; HIV Infections	Hoffmann-La Roche
NCT00004573	UNKNOWN	Cytomegalovirus Infections	National Center for Research Resources (NCRR)
NCT00016068	COMPLETED	Infection	Fred Hutchinson Cancer Center	2001-01	PHASE3
NCT00001034	COMPLETED	Cytomegalovirus Retinitis; HIV Infections; Gastrointestinal Diseases	National Institute of Allergy and Infectious Diseases (NIAID)		PHASE2
NCT00000856	WITHDRAWN	Encephalopathy; HIV Infections; Radiculitis	National Institute of Allergy and Infectious Diseases (NIAID)		PHASE1
NCT00002247	COMPLETED	Cytomegalovirus Retinitis; HIV Infections	Hoffmann-La Roche
NCT00000691	COMPLETED	Cytomegalovirus Retinitis; HIV Infections	National Institute of Allergy and Infectious Diseases (NIAID)		PHASE2
NCT00000768	COMPLETED	Colitis; HIV Infections	National Institute of Allergy and Infectious Diseases (NIAID)		PHASE1
NCT00002824	COMPLETED	Brain and Central Nervous System Tumors	Abramson Cancer Center at Penn Medicine	1996-02	PHASE1
NCT00002070	COMPLETED	Cytomegalovirus Retinitis; HIV Infections	Schering-Plough		PHASE3
NCT00000805	COMPLETED	Cytomegalovirus Infections; HIV Infections	National Institute of Allergy and Infectious Diseases (NIAID)		PHASE1
NCT00002273	COMPLETED	Colitis; HIV Infections	Hoffmann-La Roche
NCT00001062	COMPLETED	Cytomegalovirus Retinitis; HIV Infections	National Institute of Allergy and Infectious Diseases (NIAID)		PHASE1
NCT00006145	COMPLETED	Cytomegalovirus Infections; HIV Infections	National Institute of Allergy and Infectious Diseases (NIAID)	2000-08	PHASE3
NCT00002135	COMPLETED	Cytomegalovirus Retinitis; HIV Infections	Hoffmann-La Roche
NCT00002134	COMPLETED	Cytomegalovirus Retinitis; HIV Infections	Roche Global Development
NCT00002222	COMPLETED	Cytomegalovirus Retinitis; HIV Infections	Hoffmann-La Roche
NCT00374686	COMPLETED	Cytomegalovirus Infection	Washington University School of Medicine	2003-03
NCT00005025	UNKNOWN	Fallopian Tube Cancer; Ovarian Cancer; Primary Peritoneal Cavity Cancer	John Stoddard Cancer Center at Iowa Methodist Medical Center	2000-06	PHASE2
NCT00006216	UNKNOWN	Malignant Mesothelioma	Louisiana State University Health Sciences Center in New Orleans	1997-08	PHASE1
NCT00002024	COMPLETED	Cytomegalovirus Infections; HIV Infections	Hoffmann-La Roche
NCT00000698	COMPLETED	Cytomegalovirus Retinitis; HIV Infections	National Institute of Allergy and Infectious Diseases (NIAID)		PHASE3
NCT00000697	WITHDRAWN	Cytomegalovirus Retinitis; HIV Infections	National Institute of Allergy and Infectious Diseases (NIAID)		PHASE2
NCT00000118	COMPLETED	HIV Infections; Acquired Immunodeficiency Syndrome; Cytomegalovirus Retinitis	National Eye Institute (NEI)	1992-10	PHASE3
NCT00264368	TERMINATED	Acute Renal Failure; Cytomegalovirus Infections; Multi Organ Failure	University of Oslo School of Pharmacy	2005-12	PHASE4

(data from https://clinicaltrials.gov, updated on 2026-08-11)

Check the Ganciclovir sodium product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Compliance for Clinical Use

Mechanism and Biochemical Profile

Ganciclovir sodium is phosphorylated intracellularly to its active triphosphate derivative, which competitively inhibits viral DNA polymerase and incorporates into viral DNA to terminate chain elongation and halt viral replication. By suppressing viral propagation, this synthetic purine nucleoside analog prevents cytomegalovirus disease and reduces viral load in transplant recipients and immunocompromised patients.

Appendix RUO and cGMP Quality Standards

Quality Dimension	RUO (Research Use Only)	cGMP (Current Good Manufacturing Practice)
Clinical Applicability	Prohibited in human clinical trials or medical diagnostics.	Mandatory for human clinical trials (Phase I–III) and therapies.
Regulatory Status	Non-regulated grade; exempt from drug manufacturing laws.	Legally enforced by health authorities (e.g., FDA, EMA, NMPA).
Facility Environment	Unclassified analytical or research laboratories.	Validated Cleanrooms (ISO Class 5–8) with continuous monitoring.
Quality Control	Basic purity and activity testing.	Rigorous safety release testing (Sterility, Endotoxin, Mycoplasma).
Process Validation	Basic equipment calibration; no process validation required.	Full qualification (IQ/OQ/PQ) and complete batch records.
Quality Assurance	Vendor self-declared without required formal QMS.	Mandatory QA/QC unit, Change Control, CAPA, and vendor audits.
Regulatory Impact	High risk of IND rejection if used as a critical raw material.	Required for IND/NDA filings, supported by Drug Master Files (DMF).

Footnotes

Regulatory Note: Governed by FDA (21 CFR Parts 210/211/312), EMA (EudraLex Vol 4), ICH Guidelines (E6/Q7/Q9/Q10), and compendial standards (USP <71>/<85>/<1043>).