CAS No. 548-83-4
Batch:
Purity:99.99
Chemical Structure
Check the
Galangin
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
Chemical Information
| IUPAC Name | 3,5,7-trihydroxy-2-phenylchromen-4-one | |
|---|---|---|
| CAS Number | 548-83-4 | |
| Molecular Formula |
C15H10O5 |
|
| Molecular Weight (MW) | 270.24 | |
| SMILES | C1=CC=C(C=C1)C2=C(C(=O)C3=C(C=C(C=C3O2)O)O)O | |
| InChIKey | VCCRNZQBSJXYJD-UHFFFAOYSA-N |
Biological Activity
Galangin is a naturally occurring flavonoid that acts as an antioxidant, a cytochrome P450 1A1 (CYP1A1) inhibitor, and a modulator of the aryl hydrocarbon receptor (AhR). By regulating AhR signaling and inhibiting CYP1A1 expression, galangin suppresses xenobiotic metabolism and cellular oxidative stress. Downstream, galangin induces cellular protective antioxidant defenses and exhibits potential chemopreventive activities across various cell models.
How to Prepare Stock Solution?
|
Concentration
Volume
Mass
|
|---|
Solubility
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
54 mg/mL
(199.82 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 30 mg/mL |
| Water | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
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Note: Technical data last updated: Sep 1, 2026.