CAS No. 322455-70-9
Chemical Structure
Check the
FSL-1
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
Chemical Information
| IUPAC Name | (3S)-4-[(2S)-2-[[(2S)-6-amino-1-[[(2S)-1-[(2S)-2-[[(2S)-6-amino-1-[[(2S)-1-[[(1S)-1-carboxy-2-phenylethyl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]carbamoyl]pyrrolidin-1-yl]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]carbamoyl]pyrrolidin-1-yl]-3-[[2-[[(2R)-2-amino-3-[2,3-di(hexadecanoyloxy)propylsulfanyl]propanoyl]amino]acetyl]amino]-4-oxobutanoic acid | |
|---|---|---|
| CAS Number | 322455-70-9 | |
| Molecular Formula |
C₈₄H₁₄₀N₁₄O₁₈S |
|
| Molecular Weight (MW) | 1666.16 | |
| InChIKey | VJJLLNHELGKSNA-YWKNMTRCSA-N |
Biological Activity
FSL-1 is a synthetic, bacterial-derived Toll-like receptor 2/6 (TLR2/6) agonist. Upon binding to the TLR2/6 heterodimer complex, FSL-1 stimulates MyD88-dependent downstream signaling pathways, leading to robust NF-κB activation and downstream transcription of inflammatory genes. This cascade induces the secretion of proinflammatory cytokines and chemokines, triggering protective innate mucosal immune responses that ultimately enhance host resistance to experimental HSV-2 infection. [1]
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Note: Technical data last updated: Sep 1, 2026.