CAS No. 1158383-34-6
Batch:
Purity:99.84
Chemical Structure
Check the
FSG67
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | 2-(nonylsulfonylamino)benzoic acid | |
|---|---|---|
| CAS Number | 1158383-34-6 | |
| Molecular Formula |
C16H25NO4S |
|
| Molecular Weight (MW) | 327.44 | |
| InChIKey | WNFXEGWGYFRRJC-UHFFFAOYSA-N |
FSGis a small-molecule inhibitor of glycerol 3-phosphate acyltransferase (GPAT). By blunting GPAT enzyme activity, FSGalters glycerolipid biosynthesis and significantly increases oxidative metabolism in mature adipocytes. Furthermore, in preclinical models, FSG67 blunts liver regeneration following acetaminophen overdose by altering glycogen synthase kinase-3β (GSK3β) activity and canonical Wnt/β-catenin signaling, leading to reduced expression of pro-regenerative downstream targets. [1][2]
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Concentration
Volume
Mass
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Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
65 mg/mL
(198.5 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 65 mg/mL |
| Water | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.