CAS No. 158930-17-7
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Chemical Structure
Check the
Frovatriptan succinate hydrate
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| CAS Number | 158930-17-7 | |
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| Molecular Formula |
C14H17N3O.C4H6O4.H2O |
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| Molecular Weight (MW) | 379.41 |
Frovatriptan succinate hydrate is a selective agonist targeting serotonin 5-HT1B and 5-HT1D receptors. Activation of 5-HT1B and 5-HT1D receptors promotes G protein-coupled receptor signaling, leading to vasoconstriction of cranial blood vessels and inhibition of pro-inflammatory neuropeptide release from trigeminal sensory nerves. These downstream cellular mechanisms effectively suppress neurogenic inflammation and vascular dilation in intracranial pathways. [1][2]
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All in vitro solubility values are batch-tested experimental data (non-literature values).
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Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
- Frovatriptan succinate hydrate Solubility in DMSO
- Frovatriptan succinate hydrate Stock Solution
- Frovatriptan succinate hydrate Storage
- Frovatriptan succinate hydrate Stability
- Frovatriptan succinate hydrate Molecular Weight
- Frovatriptan succinate hydrate Chemical Structure (2D and 3D)
- Frovatriptan succinate hydrate SDS｜MSDS
Note: Technical data last updated: Sep 1, 2026.