CAS No. 103141-09-9
Batch:
Purity:99.57
Chemical Structure
Check the
FPL 62064
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | N-(4-methoxyphenyl)-1-phenylpyrazol-3-amine | |
|---|---|---|
| CAS Number | 103141-09-9 | |
| Molecular Formula |
C16H15N3O
|
|
| Molecular Weight (MW) | 265.31 | |
| SMILES | COC1=CC=C(C=C1)NC2=NN(C=C2)C3=CC=CC=C3 | |
| InChIKey | WKLGNFJHVJIZPK-UHFFFAOYSA-N |
FPL 62064 is a synthetic dual inhibitor targeting 5-lipoxygenase (5-LOX) and cyclooxygenase (COX). By simultaneously suppressing 5-LOX and COX enzymatic activities, FPL 62064 blocks the biosynthesis of both leukotrienes and prostaglandins within arachidonic acid metabolic pathways. This dual pathway inhibition downstream attenuates mediator-driven inflammatory signaling and suppresses cellular inflammatory phenotypes, demonstrating potent anti-inflammatory activity in preclinical models.
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
53 mg/mL
(199.76 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 20 mg/mL |
| Water | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.