CAS No. 957485-64-2
Batch:
Purity:99.83
Chemical Structure
Check the
FPH2 (BRD-9424)
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
Chemical Information
| CAS Number | 957485-64-2 | |
|---|---|---|
| Molecular Formula |
C14H16ClN5O2S |
|
| Molecular Weight (MW) | 353.83 | |
| SMILES | CCN1C=C(C(=N1)C(=O)N)NC(=S)NC2=C(C=CC(=C2)Cl)OC |
Biological Activity
FPH2 (BRD-9424) is a small-molecule activator that promotes the functional expansion and maturation of hepatocytes. It facilitates the proliferation and differentiation of induced pluripotent stem cell-derived hepatocytes and primary human hepatocytes without inducing dedifferentiation. By modulating hepatic lineage-specific signaling, FPH2 enhances liver-specific functional phenotypes, including albumin secretion and metabolic enzyme activity, supporting liver cell modeling and regenerative medicine applications. [1]
How to Prepare Stock Solution?
|
Concentration
Volume
Mass
|
|---|
Solubility
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
70 mg/mL
(197.83 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Pre-aliquoted for Longevity: Solid-state aliquots offer longer shelf life compared to stock solutions.
Looking for a specific aliquot size? Contact your local sales representative or orders@selleckchem.com.
Reference
Jump to
Note: Technical data last updated: Sep 1, 2026.