CAS No. 708219-39-0
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| IUPAC Name | 2-(5-chloro-2-methyl-N-methylsulfonylanilino)-N-(2,6-difluorophenyl)acetamide | |
|---|---|---|
| CAS Number | 708219-39-0 | |
| Molecular Formula |
C16H15ClF2N2O3S |
|
| Molecular Weight (MW) | 388.82 | |
| SMILES | CC1=C(C=C(C=C1)Cl)N(CC(=O)NC2=C(C=CC=C2F)F)S(=O)(=O)C | |
| InChIKey | WAOBCCBUTHNTFO-UHFFFAOYSA-N |
FPH1 is a small molecule promoter of hepatocyte expansion that facilitates the proliferation and functional maturation of induced pluripotent stem cell (iPSC)-derived hepatocytes. By driving the cell cycle and self-renewal pathways, FPH1 enhances the generation of functional liver cells without inducing dedifferentiation. This compound supports downstream hepatocyte-specific phenotypes, including albumin secretion and metabolic gene expression, providing a valuable tool for liver tissue engineering and regenerative medicine studies. [1]
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Concentration
Volume
Mass
|
|---|
| Solvent | Solubility & Note |
|---|---|
| DMSO |
78 mg/mL
(200.6 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
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