CAS No. 81525-13-5

Batch: Purity:99.64
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Forsythoside B Chemical Structure
Chemical Structure
Check the Forsythoside B product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

CAS Number 81525-13-5
Molecular Formula

C34H44O19
Molecular Weight (MW) 756.70
SMILES CC1C(C(C(C(O1)OC2C(C(OC(C2OC(=O)C=CC3=CC(=C(C=C3)O)O)COC4C(C(CO4)(CO)O)O)OCCC5=CC(=C(C=C5)O)O)O)O)O)O

Ordering Information

Biological Activity

Forsythoside B is a naturally occurring phenylethanoid glycoside possessing potent neuroprotective, anti-inflammatory, antioxidant, and antisepsis properties. It regulates the NF-κB signaling pathway by inhibiting IκB degradation and suppressing downstream expression of pro-inflammatory cytokines, including TNF-α and IL-6. Through these molecular actions, Forsythoside B attenuates systemic and neuroinflammatory responses while alleviating memory impairment in animal models.

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 100 mg/mL (132.15 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Water 100 mg/mL
Ethanol 100 mg/mL
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.