CAS No. 79916-77-1

Batch: Purity:99.91
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Forsythoside A Chemical Structure
Chemical Structure
Check the Forsythoside A product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

IUPAC Name [(2R,3S,4R,5R,6R)-6-[2-(3,4-dihydroxyphenyl)ethoxy]-4,5-dihydroxy-2-[[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxymethyl]oxan-3-yl] (E)-3-(3,4-dihydroxyphenyl)prop-2-enoate
CAS Number 79916-77-1
Molecular Formula

C29H36O15
Molecular Weight (MW) 624.59
SMILES CC1C(C(C(C(O1)OCC2C(C(C(C(O2)OCCC3=CC(=C(C=C3)O)O)O)O)OC(=O)C=CC4=CC(=C(C=C4)O)O)O)O)O
InChIKey DTOUWTJYUCZJQD-UJERWXFOSA-N

Biological Activity

Forsythoside A is a natural phenylethanoid glycoside isolated from Forsythia fructus with anti-inflammatory, antibacterial, and immunomodulatory properties. It suppresses lipopolysaccharide-induced inflammatory responses by inhibiting the activation of the NF-kB signaling pathway, leading to reduced production of pro-inflammatory cytokines including TNF-a, IL-1b, and IL-6. These downstream cellular effects mitigate tissue inflammation and regulate immune cell function. [1]

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 100 mg/mL (160.1 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Water 100 mg/mL
Ethanol 100 mg/mL
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

Reference

[1] int. forest. rev. 2012;14(3):391-398.

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Note: Technical data last updated: Sep 1, 2026.