CAS No. 54910-89-3
Batch:
Purity:99.01
Chemical Structure
Check the
Fluoxetine
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine | |
|---|---|---|
| CAS Number | 54910-89-3 | |
| Molecular Formula |
C17H18F3NO |
|
| Molecular Weight (MW) | 309.33 | |
| InChIKey | RTHCYVBBDHJXIQ-UHFFFAOYSA-N |
Fluoxetine is a selective serotonin reuptake inhibitor (SSRI) that targets the serotonin transporter (SERT). By inhibiting SERT, fluoxetine blocks the reuptake of 5-hydroxytryptamine (5-HT) into presynaptic neurons, resulting in increased extracellular serotonin levels and enhanced serotonergic neurotransmission. In addition to modulating neurochemical signaling pathways, fluoxetine exhibits neuroprotective properties and suppresses neuroinflammatory responses. [1][2]
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| Ethanol | 62 mg/mL |
| DMSO |
61 mg/mL
(197.2 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.