CAS No. 86393-33-1
Batch:
Purity:98
Chemical Structure
Check the
Fluoroquinolonic Acid
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
Chemical Information
| CAS Number | 86393-33-1 | |
|---|---|---|
| Molecular Formula |
C13H9ClFNO3 |
|
| Molecular Weight (MW) | 281.67 | |
| SMILES | C1CC1N2C=C(C(=O)C3=CC(=C(C=C32)Cl)F)C(=O)O |
Biological Activity
Fluoroquinolonic acid is a quinolone-derived antimicrobial agent and key chemical precursor in antibiotic synthesis. As a core fluoroquinolone derivative, the compound targets bacterial type II topoisomerase enzymes, specifically DNA gyrase and topoisomerase IV. By stabilizing cleavage complexes during bacterial DNA replication and transcription, it blocks nucleic acid synthesis and disrupts genome integrity, ultimately leading to the inhibition of bacterial growth and cellular survival. [1]
How to Prepare Stock Solution?
|
Concentration
Volume
Mass
|
|---|
Solubility
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
25 mg/mL
(88.75 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Reference
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Note: Technical data last updated: Sep 1, 2026.