CAS No. 127-31-1

Fludrocortisone Chemical Structure
Chemical Structure
Check the Fludrocortisone product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

CAS Number 127-31-1
Molecular Formula

C21H29FO5

Molecular Weight (MW) 380.45

Ordering Information

Biological Activity

Fludrocortisone is a synthetic corticosteroid that functions as a potent mineralocorticoid receptor agonist. Upon binding and activating the mineralocorticoid receptor, it regulates downstream gene expression involved in electrolyte transport and fluid balance. This activation enhances sodium reabsorption and potassium excretion, while increasing vascular pressor sensitivity to circulating catecholamines and angiotensin, thereby modulating central adrenergic signaling and systemic intravascular volume. [1]

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Note: Technical data last updated: Sep 1, 2026.