CAS No. 2295-58-1
Batch:
Purity:99.62
Chemical Structure
Check the
Flopropione
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| CAS Number | 2295-58-1 | |
|---|---|---|
| Molecular Formula |
C9H10O4 |
|
| Molecular Weight (MW) | 182.17 | |
| SMILES | CCC(=O)C1=C(C=C(C=C1O)O)O |
Flopropione is a synthetic phloroglucinol derivative that functions as an antispasmodic agent and a 5-HT1A receptor antagonist. By inhibiting 5-HT1A receptor-mediated signaling pathways, flopropione modulates serotonin-induced cellular responses and smooth muscle tone. This antagonism contributes to the relaxation of gastrointestinal and biliary smooth muscles, suppressing involuntary spasms and regulating motility across visceral tissue systems. [1]
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
36 mg/mL
(197.61 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 36 mg/mL |
| Water | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Pre-aliquoted for Longevity: Solid-state aliquots offer significantly longer shelf life compared to stock solutions, ensuring maximum stability for every use.
Looking for a specific aliquot size? Reach out to your local sales representative or contact us at orders@selleckchem.com.
Note: Technical data last updated: Sep 1, 2026.