CAS No. 167933-07-5
Batch:
Purity:99.61
Chemical Structure
Check the
Flibanserin
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| CAS Number | 167933-07-5 | |
|---|---|---|
| Molecular Formula |
C20H21F3N4O |
|
| Molecular Weight (MW) | 390.40 | |
| SMILES | C1CN(CCN1CCN2C3=CC=CC=C3NC2=O)C4=CC=CC(=C4)C(F)(F)F |
Flibanserin (BIMT-17) is a nonhormonal, centrally acting compound that functions as a postsynaptic 5-HT1A receptor agonist and a 5-HT2A receptor antagonist. By modulating central serotonergic neurotransmission, it alters downstream dopamine and norepinephrine release in the prefrontal cortex while reducing serotonin levels. These neurochemical shifts mediate functional central nervous system effects and modulate behavioral responsiveness in rodent models. [1]
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
78 mg/mL
(199.79 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 23 mg/mL |
| Water | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.