CAS No. 11078-21-0
Chemical Structure
Check the
Filipin complex
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | (3R,4S,6S,8S,10R,12R,14R,16S,17E,19E,21E,23E,25E,27S,28R)-4,6,8,10,12,14,16,27-octahydroxy-3-[(1R)-1-hydroxyhexyl]-17,28-dimethyl-1-oxacyclooctacosa-17,19,21,23,25-pentaen-2-one | |
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| CAS Number | 11078-21-0 | |
| Molecular Formula | ||
| Molecular Weight (MW) | N/A | |
| InChIKey | IMQSIXYSKPIGPD-YQRUMEKGSA-N |
Filipin complex is a polyene macrolide antibiotic and fluorescent probe that targets membrane cholesterol by sequestering unesterified sterols into distinct complexes. By disrupting cholesterol-rich membrane microdomains, it inhibits viral infection pathways, notably reducing porcine reproductive and respiratory syndrome virus replication. Additionally, filipin complex impairs lysosomal cholesterol trafficking, serving as a histochemical tool to visualize unesterified cholesterol accumulation in cellular models of Niemann-Pick disease type C and related neurodegenerative disorders. [1][2]
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Note: Technical data last updated: Sep 1, 2026.