CAS No. 1391934-98-7
Batch:
Purity:99.26
Chemical Structure
Check the
FIDAS-5
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | 4-[(E)-2-(2-chloro-6-fluorophenyl)ethenyl]-N-methylaniline | |
|---|---|---|
| CAS Number | 1391934-98-7 | |
| Molecular Formula |
C15H13ClFN |
|
| Molecular Weight (MW) | 261.72 | |
| InChIKey | KXVXICBOMOGFMH-JXMROGBWSA-N |
FIDAS-5 is a potent and orally active inhibitor of methionine S-adenosyltransferase 2A (MAT2A) with an IC50 value of. FIDAS-5 effectively competes against S-adenosylmethionine (SAM) for MAT2A binding, thereby disrupting SAM production and altering cellular methionine metabolism. Through this target inhibition, FIDAS-5 represses colon cancer cell proliferation and exhibits robust anticancer activity.
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Concentration
Volume
Mass
|
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Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
200 mg/mL
(764.17 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 52 mg/mL |
| Water | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.