CAS No. 2719-05-3

Batch: Purity:99.5
FH1 Chemical Structure
Chemical Structure
Check the FH1 product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

IUPAC Name N-[4-[(4-acetamidophenyl)methyl]phenyl]acetamide
CAS Number 2719-05-3
Molecular Formula

C17H18N2O2

Molecular Weight (MW) 282.34
SMILES CC(=O)NC1=CC=C(C=C1)CC2=CC=C(C=C2)NC(=O)C
InChIKey OEXMNSOPAKOPEF-UHFFFAOYSA-N

Ordering Information

Biological Activity

FH1 is a small-molecule differentiation inducer that promotes the maturation and functional differentiation of induced pluripotent stem cell (iPSC)-derived hepatocytes. Treatment with FH1 enhances hepatocyte-specific gene expression and hepatic functional phenotypes, including albumin secretion and metabolic activity. These effects support the generation of functionally mature hepatocytes for in vitro disease modeling, drug toxicity screening, and regenerative medicine applications. [1]

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 56 mg/mL (198.34 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Water Insoluble
Ethanol Insoluble
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.