CAS No. 83799-24-0
Batch:
Purity:99.89
Chemical Structure
Check the
Fexofenadine
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| CAS Number | 83799-24-0 | |
|---|---|---|
| Molecular Formula |
C32H39NO4 |
|
| Molecular Weight (MW) | 501.66 |
Fexofenadine is a second-generation antagonist of the histamine H1 receptor. Downstream of receptor blockade, it attenuates allergic inflammatory responses by inhibiting inducible nitric oxide synthase (iNOS) gene expression and reducing nitric oxide production. Furthermore, fexofenadine exhibits selective cyclooxygenase-2 (COX-2) inhibitory activity, suppressing pro-inflammatory pathways to mitigate eosinophilia and systemic anaphylaxis associated with allergic conditions. [1][2]
|
Concentration
Volume
Mass
|
1 mg | 5 mg | 10 mg |
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
25 mg/mL
(49.83 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.