CAS No. 458-36-6

Batch: Purity:99.99
Ferulaldehyde Chemical Structure
Chemical Structure
Check the Ferulaldehyde product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

CAS Number 458-36-6
Molecular Formula

C10H10O3

Molecular Weight (MW) 178.18
SMILES COC1=C(C=CC(=C1)C=CC=O)O

Ordering Information

Biological Activity

Ferulaldehyde is a natural phenolic compound and intermediate of intestinal polyphenol metabolism that acts as an anti-inflammatory and antioxidant agent. It suppresses the NF-kB and MAPK signaling pathways, leading to downregulation of inducible nitric oxide synthase and cyclooxygenase-2 expression. Furthermore, ferulaldehyde attenuates oxidative stress by promoting Nrf2 pathway activation, thereby reducing cellular inflammatory damage.

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 36 mg/mL (202.04 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Ethanol 36 mg/mL
Water Insoluble
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.