CAS No. 58306-30-2
Batch:
Purity:99.93
Chemical Structure
Check the
Febantel
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
Chemical Information
| IUPAC Name | methyl N-[N'-[2-[(2-methoxyacetyl)amino]-4-phenylsulfanylphenyl]-N-methoxycarbonylcarbamimidoyl]carbamate | |
|---|---|---|
| CAS Number | 58306-30-2 | |
| Molecular Formula |
C20H22N4O6S |
|
| Molecular Weight (MW) | 446.48 | |
| SMILES | COCC(=O)NC1=C(C=CC(=C1)SC2=CC=CC=C2)N=C(NC(=O)OC)NC(=O)OC | |
| InChIKey | HMCCXLBXIJMERM-UHFFFAOYSA-N |
Biological Activity
Febantel is a pro-benzimidazole anthelmintic agent that functions as a prodrug. It undergoes biotransformation to produce active metabolites, including fenbendazole and oxfendazole. These active metabolites selectively bind to helminth β-tubulin, disrupting microtubule polymerization and assembly. This inhibition impairs cellular structure, glucose uptake, and energy metabolism in susceptible parasites, ultimately leading to parasite immobilization and mortality.
How to Prepare Stock Solution?
|
Concentration
Volume
Mass
|
|---|
Solubility
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
89 mg/mL
(199.33 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
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Note: Technical data last updated: Sep 1, 2026.