CAS No. 24211-30-1

Batch: Purity:99.98
Farrerol Chemical Structure
Chemical Structure
Check the Farrerol product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

IUPAC Name (2S)-5,7-dihydroxy-2-(4-hydroxyphenyl)-6,8-dimethyl-2,3-dihydrochromen-4-one
CAS Number 24211-30-1
Molecular Formula

C17H16O5

Molecular Weight (MW) 300.31
SMILES CC1=C(C(=C2C(=C1O)C(=O)CC(O2)C3=CC=C(C=C3)O)C)O
InChIKey DYHOLQACRGJEHX-ZDUSSCGKSA-N

Ordering Information

Biological Activity

Farrerol is a natural flavanone that functions as an anti-inflammatory and antioxidant agent. It suppresses lipopolysaccharide-induced inflammatory responses by inhibiting the activation of NF-κB and MAPK signaling pathways. Downstream, farrerol attenuates the phosphorylation of ERK, p38, and JNK, leading to reduced expression of pro-inflammatory cytokines including TNF-α, IL-6, and IL-1β. Through these mechanisms, farrerol mitigates inflammatory injury and cellular oxidative stress.

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 60 mg/mL (199.79 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Ethanol 60 mg/mL
Water Insoluble
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.